Explorative review of key proteins in Impulsive control disorders among Parkinson’s disease patients

Jaspal Singh

Abstract


As stated by (Weintraub D et al., 2010) 13.6% of those individuals with Parkinson’s disease (PD) have one or more forms of impulse control disorders (ICD), whilst the prevalence is greatest in those taking dopamine agonists. Taking a stepwise approach, the current review looks to evaluate the evidence of dopamine 3 receptor’s importance to impulsive control disorders amongst those with PD. In conclusion the literature indicates a central role played by the DRD3 receptor whereby the use of specific DRD3 agonists ultimately led to impulsive control disorders. 


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